Sitagliptin 50 mg, Glimepiride 1 mg, Metformin 500 mg

Generic Sitagliptin 50 mg + Glimepiride 1 mg + Metformin 500 mg is a prescription combination tablet used for blood sugar management in adults with type 2 diabetes mellitus, especially when one or two medicines are not achieving consistent control. Doctors often select this specific strength when they want a balanced approach with a lower dose of glimepiride, while still supporting steady daily glucose regulation.

Metformin helps reduce glucose production in the liver and improves how the body uses insulin, which supports better baseline control. Sitagliptin improves glucose-dependent insulin release and helps reduce excess glucagon after meals, which can smooth post-meal rises. Glimepiride increases insulin release from the pancreas, so it supports stronger glucose lowering, but it also brings a risk of low blood sugar if meals are skipped, delayed, or reduced. Because of this, routine meal timing and monitoring become important.

Many patients take this tablet with food to improve stomach tolerance. Check glucose regularly, especially in the first weeks or when diet and activity patterns change. Speak to your doctor if you notice sweating, tremors, sudden hunger, dizziness, confusion, or repeated low readings. Also report persistent nausea, vomiting, or unusual tiredness. Your doctor may advise you for a periodic kidney function monitoring and overall blood test for better kidney and liver health.