Metformin Hydrochloride 500 mg + Gliclazide 80 mg

Generic Metformin Hydrochloride 500 mg + Gliclazide 80 mg is a prescription combination used for blood sugar management in adults with type 2 diabetes mellitus, particularly when diet, activity, and metformin alone are not achieving target readings. Doctors often use this combination when both fasting and post-meal control need improvement, or when a higher sulfonylurea strength is required to reach goals.

Why doctors precribe it?

Metformin is commonly used as a foundation medicine, while gliclazide is added when additional glucose lowering is needed. The 80 mg strength is generally used when a stronger insulin-release effect is required. Clinicians may select it for patients who have persistent elevated readings despite consistent lifestyle measures, or when step-up therapy is planned under follow-up.

How it supports control?

Metformin reduces glucose production in the liver and improves insulin sensitivity, supporting baseline and fasting control. Gliclazide increases insulin release from the pancreas, which can reduce glucose levels more strongly, particularly around meals. Because it increases insulin output, gliclazide can lead to low blood sugar if meals are delayed, skipped, or reduced, or if physical activity increases suddenly without adjustment.

How to take?

Take exactly as prescribed, commonly with meals to reduce stomach upset and align gliclazide action with food intake. Maintain consistent meal timing. If your product is modified-release, swallow it whole and do not crush or chew. If a dose is missed, follow your doctor’s instructions rather than taking an extra dose close to the next scheduled one.

Who is prescribed Metformin Hydrochloride 500 mg + Gliclazide 80 mg?

• Commonly prescribed for: adults with type 2 diabetes mellitus needing stronger add-on therapy, mixed fasting and post-meal elevation, or step-up plans
• Use caution if: kidney impairment, liver impairment, irregular eating patterns, older age with fall risk, or use of multiple glucose-lowering medicines
• Inform your doctor if you fast frequently, drink alcohol regularly, or have recurrent vomiting or diarrhoea

Suggestion

• Doctors typically monitor glycated hemoglobin, kidney function, and home glucose logs
• Seek medical advice for sweating, tremor, confusion, fainting, repeated low readings, or persistent stomach upset

Health suggestion for diabetes when taking Metformin Hydrochloride + Gliclazide

• Keep meals regular and do not skip breakfast; low blood sugar risk increases with missed meals
• Prefer high-fibre carbohydrates and adequate protein to reduce post-meal spikes
• Monitor fasting and post-meal glucose more closely after dose changes or increased activity
• Carry a quick glucose source if your doctor advises for low blood sugar episodes